Tumour necrosis factor alpha in severe congestive cardiac failure.
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چکیده
منابع مشابه
Tumor necrosis factor-alpha and interleukin-10 genotypes in congestive heart failure.
7. Montgomery HE, Clarkson P, Dollery CM, Prasad K, Losi M-A, Hemingway H, Statters D, Jubb M, Girvain M, Varnava A, World M, Deanfield J, Talmud P, McEwan JR, McKenna WJ, Humphries S. Association of angiotensin-converting enzyme gene I/D polymorphism with change in left ventricular mass in response to physical training. Circulation. 1997;96:741–747. Increased Membrane and Soluble P-Selectin in...
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Accepted 28 February 1996 An 80-year-old man presented with a two-week history of anorexia, malaise, peripheral and scrotal oedema and shortness of breath. He had no cardiac history and consumed very little alcohol. He had been active prior to the onset of symptoms and had been playing golf regularly. Clinical examination revealed a sinus tachycardia of 112 beats/min, a jugular venous pressure ...
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Heart failure is a systemic disorder characterised by tissue hypoxia and secondary organ dysfunction which occurs in response to various myocardial insults that include ischaemia, viral infections, and toxins. In addition to maladaptive neurohumoral activation, heart failure is associated with an inflammatory state that appears to have a detrimental effect on cardiac function and prognosis. Thi...
متن کاملIncreased expression of tumor necrosis factor-alpha converting enzyme and tumor necrosis factor-alpha in peripheral blood mononuclear cells in patients with advanced congestive heart failure.
BACKGROUND Tumor necrosis factor-alpha converting enzyme (TACE) has recently been identified as a metalloproteinase-disintegrin, which converts pro-tumor necrosis factor-alpha (TNF-alpha) to the mature form, and is an important mediator in the pathogenesis of CHF. AIMS In order to establish the importance of TACE in the regulation of TNF-alpha synthesis in peripheral blood mononuclear cells (...
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ژورنال
عنوان ژورنال: Heart
سال: 1993
ISSN: 1355-6037
DOI: 10.1136/hrt.70.2.141